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The genetics of clubfoot

By Jay D. Lenn

OREF-funded study helps to further understanding of foot disorder

Clubfoot is a common musculoskeletal disorder, but in many cases, the cause is unknown. Several lines of evidence—family history, twin studies, and varying prevalence rates among different ethnic groups—point to a genetic cause or a genetic susceptibility to the disorder, but the role played by genes is not clear.

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