Research Development Committee

AAOS/NIH Research Symposia: Osteolysis and Implant Wear: Biological, Biomedical Engineering and Surgical Principles

• Principal Investigators: Stuart Goodman MD, PhD, and Timothy Wright, PhD
• Dates: November 9-11, 2007, Austin, Texas
• Participants: Orthopaedic surgeons, Young Investigators, researchers, industry representatives, and other medical specialties (by invitation only).
• Purpose of Workshop: Wear of total joint replacements and the subsequent effects of wear debris currently remain the most important problems in joint replacement surgery. Revision procedures are technically more difficult than primary procedures, have a higher complication rate, a less predictable clinical outcome and are more costly. The surgery is often accompanied by significant bone loss, necessitating the use of extensive bone grafting and special prosthetic devices. Knowledge of the basic clinical, biological, design, and material principles relevant to prosthetic wear is necessary to prevent, diagnose and treat patients with wear-associated problems.
• Overview of Topics:
• Clinical, biological, engineering and material questions in implant wear
• Differences among gender, race, and ethnicity in regard to these questions
• The results of the IW symposium will be published in a Special Issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) in mid-2008.
• Final Symposium Agenda
• In the News:
• Combating osteolysis and implant wear (October 2007)
• Symposium focuses on osteolysis and implant wear (January 2008)
• Biological data shed light on osteolysis and implant wear (January 2008)
• Can surgeons win the fight against osteolysis and implant wear? (February 2008)
• ORS Young Investigator Attendees:
• James Huddleston, MD (Stanford University School of Medicine)
• Francis Y. Lee, MD (Columbia University)
• Amanda D. Marshall, MD (University of Texas Health Science Center - San Antonio)
• Ebru Oral, PhD (Massachusetts General Hospital / Harvard Medical School)
• Jeremy Wilkinson, PhD, FRCS (Orth) (University of Sheffield – United Kingdom)
• IW Symposium Industry Sponsors:
• DePuy–Silver Level
• DePuy Spine-Bronze Level
• Smith & Nephew–Bronze Level
• Stryker Orthopaedics–Bronze Level
• Synthes–Bronze Level
• Zimmer–Bronze Level
• IW Symposium Collaborative Partners:
• American Association of Hip and Knee Surgeons (AAHKS)
• The Knee Society
• Orthopaedic Research and Education Foundation (OREF)
• Orthopaedic Research Society (ORS)
• The IW symposium is partially funded by a National Institutes of Health (NIH) U-13 conference support grant (1U13AR055732-01) through the NIAMS.