Second Look

If you missed these news items the first time around, AAOS Now gives you a second chance to review them. Headline News Now, the AAOS thrice-weekly, online update of news

of interest to orthopaedic surgeons, brings you the latest on clinical, socioeconomic, and political issues, as well as important announcements from AAOS.

FDA alert: Bisphosphonates linked to severe musculoskeletal pain
The U.S. Food and Drug Administration (FDA) has issued a MedWatch safety alert regarding the possibility of severe and sometimes incapacitating bone, joint, and/or musculoskeletal pain in patients taking bisphosphonates. Although severe musculoskeletal pain is included in the prescribing information for all bisphosphonates, the association between bisphosphonates and severe musculoskeletal pain may be overlooked by healthcare professionals, delaying diagnosis, prolonging pain and/or impairment, and necessitating the use of analgesics. The FDA recommends that healthcare professionals consider whether bisphosphonate use might be responsible for severe musculoskeletal pain in patients who present with these symptoms, and consider temporary or permanent discontinuation of the drug.

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