What can mice teach us about age-related skeletal disorders?

By Mary Ann Porucznik

Genetic studies shed light on musculoskeletal conditions

The prevalence of bone and cartilage disorders increases with age, but aging alone doesn’t explain their development. By studying mouse genetics, the winners of the Kappa Delta Ann Doner Vaughan Award hoped to clarify the molecular background of several degenerative skeletal disorders, including osteoporosis, ossification of the posterior longitudinal ligament of the spine (OPLL), bone fracture healing, and osteoarthritis (OA).

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