Registry study of knee replacements finds increase in VTE over decade

By Terry Stanton

Despite chemical prophylaxis, final rate may be considered “high”

Advances in thromboprophylaxis and improved adherence to prophylactic guidelines should theoretically lead to lower rates of venous thromboembolism (VTE). However, a large-scale Danish study published in the July 6 issue of The Journal of Bone and Joint Surgery–American shows that the incidence of VTE among knee arthroplasty patients actually increased over the 10-year study period (1997–2007), from 0.82 percent in the first 3 years to 1.32 percent in the final 3 years, when more than half the surgeries were performed.

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