Margins in sarcoma: Up for debate

By Maureen Leahy

Where do you cut to avoid damage and minimize recurrence?

Standard treatment for primary soft-tissue sarcomas involves surgical excision of the tumor with a margin of surrounding tissue (Fig. 1). During resection, the surgeon also seeks to avoid damage to nearby structures, such as bone, nerves, and blood vessels. Unfortunately, no consensus exists as to what constitutes an adequate surgical margin.

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