Engineering Periosteum to Promote Bone Graft Healing

OREF grant recipient aims to reverse the failures of allografts

Catherine Rategan

Failure rates are sure to weigh on the minds of patients in need of a bone graft. Studies have found that half of all allografts following tumor resection fail in the first 5 years. At 10 years, that statistic rises to 60 percent. Moreover, 75 percent of nonfatal war wounds are injuries of the extremities that involve infected critical-size defects.

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