Unlocking the Biology of NBPI

OREF grant recipient investigates neonatal brachial plexus injury

Sharon Johnson

Neonatal brachial plexus injury (NBPI) is the most common birth injury and the most common cause of paralysis in children. Usually diagnosed at birth, NBPI is characterized by a loss of movement or weakness in the arm or hand due to damaged nerves around the shoulder. Most children with NBPI recover, but 20 percent to 30 percent sustain permanent disability. In those who do not recover, the weakness can be complicated by joint contractures that persist even if the nerves are repaired.

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