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The Role of Platelet-Rich Plasma Injection

January 01, 2012

Contributors: Kunal Kalra, MD; Abiola Atanda, MD; Dennis A Cardone, DO; Saqib Hasan, MD; Laith M Jazrawi, MD; Laith M Jazrawi, MD

Peer review has expired on this program. It is the viewer’s responsibility to determine the educational value of this historical content.
Peer review has expired on this program. It is the viewer’s responsibility to determine the educational value of this historical content.
Peer review has expired on this program. It is the viewer’s responsibility to determine the educational value of this historical content.

Platelet-rich plasma is defined as autologous blood with a concentration of platelets above baseline values. Surgeons have been using platelet-rich plasma in maxillofacial and plastic surgery since the 1990s. Its use in sports medicine is also growing, which is not surprising given its potential to enhance muscle and tendon healing. In vitro studies suggest that growth factors released by platelets can recruit reparative cells and may augment soft-tissue repair. Although there is minimal clinical evidence available, the use of platelet-rich plasma has increased, given its safety and the availability of new devices for outpatient preparation and delivery. The purpose of this video is to review the clinical evidence of the role of platelet-rich plasma injection in tendon problems. As the marketing of platelet-rich plasma increases, orthopaedic surgeons must be informed regarding the available preparation devices and their differences. Many controlled clinical trials are under way, but surgeons should approach clinical use cautiously until there is high-level clinical evidence supporting platelet-rich plasma efficacy.

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