Award-Winning Research Focuses on ACL Reconstruction

Investigator  honored for studies of graft placement under in vivo loading conditions

  When Louis E. DeFrate, ScD, joined the department of  orthopaedic surgery at Duke University Medical Center a decade ago, he and  colleague William E. Garrett Jr, MD,  PhD, discussed the relative lack of data on how anterior cruciate ligament  (ACL) graft placement affects joint function under in vivo loading conditions.  Soon after, with the assistance of radiologist Charles E. Spritzer, MD, Dr.  DeFrate developed groundbreaking new strategies for assessing ACL graft  placement and its effects on joint motion and cartilage thickness.

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