Brendan Shi, MD (right), with Orthopaedic Research and Education Foundation President Thomas P. Sculco, MD, FAAOS.


Published 3/8/2024

Brendan Shi, MD, Receives Third Annual OREF National Resident Champion Award

Brendan Shi, MD, of the University of California, Los Angeles, received the 2023 Richard Kyle, MD, Orthopaedic Research and Education Foundation (OREF) National Resident Champion Award Monday at the OREF Board of Trustees reception. Judges honored Dr. Shi at the third annual OREF National Resident Research Symposium in November 2023 for his presentation titled “Bisphosphonate Chaperones Effectively Target the Enthesis without Impairing Soft Tissue-to-Bone Repair Integrity.”

In addition to receiving the award, Dr. Shi is attending the AAOS Annual Meeting as OREF’s guest.

In his award-winning presentation, Dr. Shi noted that osteoadsorptive fluorogenic sentinel-3 (OFS-3), a novel compound utilizing a bisphosphonate targeting and cathepsin K-dependent release mechanism, “targets the tendon-to-bone repair site whether given locally or via systemic injection, and OFS-3 has no intrinsic negative effects on the biomechanical strength or organization of repairs.”

Dr. Shi participated in the National Resident Research Symposium after placing first at the Western Region Symposium, one of six symposia co-hosted by OREF around the United States last year. Depuy Synthes, Medacta USA, Smith & Nephew, and Zimmer Biomet sponsored the events. Judges ranked and scored the presentations, and the three top-scoring participants from each regional symposium were invited to present again at the national event.

OREF’s Resident Research Symposia provide residents with invaluable opportunities to assemble, socialize, and network with their peers while sharing their research projects. Past participants enthusiastically agree that the symposia are great experiences for all residents, whether competing or watching the presentations.

For a complete list of 2023 symposia winners, visit