AAOS Now, September 2026
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Troubling trends: Childhood obesity influences fracture risk and recovery patterns
Obesity is now among the most common chronic conditions of childhood, and its effects extend into the fracture clinic.
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GLP-1 RA medications are changing the TJR landscape
As rates of obesity have increased, so, too, has demand for total joint replacement (TJR).
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New studies link GLP-1 receptor agonist medications to tendon rupture risk and changes in bone metabolism
The use of GLP-1 receptor agonist (GLP-1 RA) medications has rapidly increased, with randomized controlled studies reporting reductions in major adverse cardiovascular events and diabetic kidney disease progression.
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GLP-1 RAs can influence fracture risk based on different medications and patient populations
The widespread use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) has facilitated large population studies examining associations between these medications and a range of health outcomes, including fracture risk.
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GLP-1 RAs may affect outcomes after tibial plateau fixation
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly encountered in orthopaedic trauma patients presenting for operative fracture fixation.