Basic Science

Editors: Scott Alan Rodeo, MD, FAAOS and Jason L. Dragoo, MD, FAAOS

Section 1: Basic Disciplines

  • Genetics, Gene Expression, and Epigenetics
  • Cell Biology, Cell Differentiation, and Skeletal Stem Cells
  • Structure, Function, and Biology of the Extracellular Matrix
  • Orthopaedic Biomaterials
  • Biomechanics
  • Developmental Biology of Musculoskeletal Tissues
  • Immunology and Inflammation
  • Cytokines
  • Stem Cells and Cell Therapy

Section 2: Structure and Function of Musculoskeletal Tissues

  • Bone Biology and Biomechanics
  • Articular Cartilage and Biomechanics
  • Biology and Biomechanics of the Meniscus and Labrum
  • Biology and Function of Nerve
  • Biology and Function of Skeletal Muscle
  • Synovial Joint Biology, Structure, Function, and Cross Talk
  • Tendon and Ligament Biology and Biomechanics

Section 3: Tissue Repair and Regeneration

  • Bone Healing and Bone Grafts
  • Cartilage Repair and Cartilage Grafts
  • Tendons and Ligaments
  • Meniscus
  • Hip Labrum
  • Skeletal Muscle
  • Peripheral Nervous System
  • Intervertebral Disk
  • Soft-Tissue Wounds
  • Orthopaedic Molecular and Cellular Biology, Genetics, and Immunology

Section 4: Pathophysiology

  • Musculoskeletal Infections and Microbiology Basic Science
  • Venous Thromboembolic Disease
  • Osteoarthritis
  • Osteonecrosis
  • Metabolic Bone Diseases
  • Stress Fractures
  • Genetic Diseases of Musculoskeletal Tissues
  • Neuromuscular Diseases
  • Peripheral Nerve and Spinal Cord Pathophysiology
  • Sex Differences

Section 5: Clinical Study Considerations

  • Research Methodology and Study Design
  • Biostatistics
  • The Product Development Process from Discovery, Through the FDA and Into the Clinic
  • Sex and Gender
  • Research Ethics