Published 8/4/2022

$50,000 OREF/AAOS Injectable Orthobiologics of Knee Osteoarthritis Grant Awarded

Study is second to be funded through partnership to address targeted clinical gaps research needs in musculoskeletal healthcare

ROSEMONT, Ill. (August 4, 2022)—The Orthopaedic Research and Education Foundation (OREF) announced today that Kyle R. Duchman, MD, of the University of Iowa, has been awarded the second OREF/AAOS Injectable Orthobiologics of Knee Osteoarthritis Grant. Dr. Duchman, who is an orthopedic surgeon and an Assistant Professor of Orthopedics and Rehabilitation at the University of Iowa Hospitals & Clinics, will serve as principal investigator (PI) for the study, “Platelet Rich Plasma for Osteoarthritis: Role of Exosomes in Effectiveness.” Joseph A. Buckwalter IV, MD, FAAOS, will serve as co-PI.

Funding for this grant was made possible through the OREF/AAOS Clinical Research Gaps Fund with contributions from the American Academy of Orthopaedic Surgeons (AAOS) and individual donors.

The $50,000 grant is the second to be awarded through a strategic partnership between OREF and AAOS, which aims to help narrow the gap between clinical research funding and prioritized clinical research needs in musculoskeletal care, including orthobiologics. The partnership identifies areas of clinical research for which there is a need for increased, targeted funding to evaluate the effectiveness of various orthopaedic interventions and improve the quality of care for patients. A request for applications (RFA) is expected to be published in November 2022 for the third grant to be funded through this partnership.

“The use of orthobiologics is of great interest to patients. It is imperative that we continue to prioritize research in this area so that orthopaedic surgeons are equipped to guide their patients in making safe and effective healthcare choices. We are excited to award this grant to Dr. Duchman and the University of Iowa,” said Thomas P. Sculco, MD, FAAOS, OREF president.

“We look forward to the research that Dr. Duchman and his team will conduct through this grant,” said Felix H. “Buddy” Savoie III, MD, FAAOS, AAOS president. “Together with our partners at OREF, we are pleased with the momentum behind the OREF/AAOS Clinical Research Gaps Fund. The knowledge we can glean as it relates to orthobiologics will play a pivotal role in guiding the highest quality of musculoskeletal care for our patients. Future funding will be key as we continue to close the gap in evidence-based orthobiologics research.” 

For more information about the AAOS’ investment in evidence-based educational content and symposia for orthobiologics, visit Donors interested in earmarking funds to further enable AAOS-prioritized clinical research needs within musculoskeletal healthcare may contribute to the OREF/AAOS Clinical Research Gaps Fund. Go to to make a secure online donation.

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The Orthopaedic Research and Education Foundation (OREF) is a charitable 501(c)(3) organization committed to improving lives by supporting excellence in orthopaedic research. OREF is dedicated to being the leader in supporting research that improves function, eliminates pain, and restores mobility, and is the premier orthopaedic organization funding research across all subspecialties. Visit or follow OREF on Twitter.

With more than 38,000 members, the American Academy of Orthopaedic Surgeons is the world’s largest medical association of musculoskeletal specialists. The AAOS is the trusted leader in advancing musculoskeletal health. It provides the highest quality, most comprehensive education to help orthopaedic surgeons and allied health professionals at every career level best treat patients in their daily practices. The AAOS is the source for information on bone and joint conditions, treatments and related musculoskeletal health care issues and it leads the health care discussion on advancing quality.

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Deanna Killackey 


Lauren Riley